Microneedle Based Sampling for Breast Cancer Tissues

نویسندگان

  • A. Hokkanen
  • I. Stuns
  • P. Schmid
  • A. Kokkonen
  • A. Steinecker
  • J. Budczies
  • P. Heimala
  • L. Hakalahti
چکیده

We have developed a microneedle based system that is capable of extracting cell membrane lipids from real breast cancer tissues. We show that it is possible to extract phosphatidylcholine (PC) and phosphoethanolamine (PE) lipids from the cancer tissue samples with the microneedle system and analyse them with mass spectrometry (MS). PC and PE lipids act as biomarkers for breast cancer. In future such system can help surgeons in their decision making during operations or they can be used as device for tissue research at high spatial resolution.

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تاریخ انتشار 2014